Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies [Microbiology]
(World News Science)

Herpesvirus item into cells requires the coordinated action of multiple virus envelope glycoproteins, including gH, gL, and gB. For EBV, the gp42 protein assembles into complexes with gHgL heterodimers and binds HLA class II to activate gB-mediated membrane fusion with B cells. EBV tropism is dictated by gp42 levels in... ......